Friday, September 30, 2016

September 30, 2016 Friday

Bedtime Story


Hans Bethe faces the 1933 Civil Service Law



In 1932 Hans Bethe took up the post of assistant professor at the University of Tubingen where Hans Geiger was the professor of experimental physics.

Very soon as per the new government orders (2 months after Adolf Hitler came to power), Hans was asked to relinquish his post.

The purpose of this new law was to "nationalize" the civil services.

In effect, any tenured civil servant who was not of Aryan descent had to immediately resign.

Soon this law would expand and apply to all the professionals throughout the country, whether government or private.

Geiger did little to support him.

Hans Bethe forced to resign returned to Sommerfeld asking him for help.

Sommerfeld spent that entire summer of 1932 trying to find positions for his Jewish students and colleagues.

He would fail of course.

German laws contrary to Indian laws are actually enforced and executed.

Hans Bethe like many other great Jewish minds realized quickly that his days in Germany are numbered.

Not only did Hitler's vitriolic speeches mesmerized the masses but even the economic policies of the Nazi Party was transforming German lives with unemployment falling faster than any other nation after the Great Depression.

This is what a German youth had to say on the effect that Adolf Hitler's speeches had on the masses:

"We would erupt into a frenzy of nationalistic pride that bordered on hysteria.

For minutes on end, we shouted at the top of our lungs, with tears streaming down our faces: Sieg Heil, Sieg Heil, Sieg Heil!

From that moment on, I belonged to Adolf Hitler, body and soul."

Employment was largely created with deficit spending and by bringing into circulation promissory notes called the Mefo Bills which in a manner of speaking was equivalent to creating money out of thin air.

Governments specially capitalistic ones have often devised ingenious ways of creating money out of nothing such as future borrowings, government bonds and bills, IOUs and what not.

At times even loaned money or debt itself has been used to create money under fanciful names such as debt restructuring.

Whether such means of creating money is legal or a financial crime depends on who does it, on what scale it is done and how much muscle power is backing it up.

So obviously if it was the German Central Bank President who issued the Mefo Bills instead of spending the limited available Reichsmark, it was deemed a legal fraud.

Whatever it was, by 1938 unemployment in the Nazi Germany was history.

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Good night mon ami and my fellow cousin ape.





The 1933 Law for the Reestablishment of the Civil Service made all Jews unemployable  



The masses were mesmerized and stood in awe of this man who had returned to them not only their jobs but a long lost pride and dignity 


Hjalmar Schacht: the chief designer of the Nazi Economy, President of the Reichsbank, Minister of Economics and the inventor of the much maligned Mefo Bill  

Thursday, September 29, 2016

September 29, 2016 Thursday

Bedtime Story



Hans Bethe and the rise of Adolf Hitler



Mathematical or theoretical physics is an extremely difficult subject.

It is even more arduous and painful to be good at it and be employed and paid for it.

Hans Bethe was one of the few handful men in West Europe and the United States who was really good at it.

Back in Munich once again under Sommerfeld but this time as an associate professor, he was given the task of supervising English speaking students from the United States and England.

One of them was Lloyd Smith from the Cornell University, Ithaca, New York.

This would prove to be a life changing acquaintance later.

Meanwhile at the age of 26 he wrote an article on the quantum mechanics of hydrogen and helium for the science journal:
Handbuch der Physik.

Its depth and breath of the subject was so staggering that even 25 years later it required very little updating for the 1959 edition.

By 1932, dark clouds had begin to gather over Europe both politically and economically.

The loss in the World War I had already brought the German Empire to its knees depriving it of all its territories and revenue.

At this time following the Wall Street crash of 1929 almost 6 million Germans were unemployed.

That translated into 30% of the nation's work force.

This was because the United States had began to pull out its loaned money from Europe on which the war devastated Germany was most dependent.

German defeat in the World War 1 was followed by an even worse kind of humiliation at the Treaty of Versailles the terms of which is consternating even today.

Then in 1932 a man rose from the ashes of humiliated Germany who would send shockwaves around the world.

That year Adolf Hitler acquired German citizenship (born in Austria-Hungary) and began his ascendancy towards absolute power over Germany.

Hitler and his socialist Nazi party initiated the labour intensive motorway program on a gigantic scale.

This led to the creation of the world's most efficient motorway system known as the autobahns.

Car production particularly that of Volkswagen (The People's Car) was turned into mass manufacturing in the lines of Henry Ford in the United States.

The German economy was transformed under Hitler though like everything it came at a price.

Persecution of minorities particularly those of Jews started on an unprecedented scale with a systematic and methodical machine like efficiency.

One of the Jews who found himself targeted was Hans Bethe.

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Good night mon ami and my fellow cousin ape.



The Humiliation that Germany had to endure created unforgettable bitterness


German Hyperinflation of 1923 was sickening



Absolutely useless German Mark of 1920s



Reichsautobahn: construction of the fabulous autobahns under the Third Reich. Hitler personally picked up the shovel on September 23, 1933 at Frankfurt as a mark of inauguration. 


Volkswagen Beetles production line under Nazi Germany   


Wednesday, September 28, 2016

September 28, 2016 Wednesday

Bedtime Story


Early Life of Hans Bethe and Bethe ansatz



The first thing that Hans Bethe was taught by Sommerfeld was an advanced course in differential equations applied in physics.

Most of us would have been bored to death.

Young Hans enjoyed it.

The next subject that Sommerfeld took up at his weekly evening seminars was the fresh paper on wave mechanics by Erwin Schrödinger that was published in 1926.

Hans was just 20 then.

This paper actually was a series of 4 papers all published in quick succession in 1926 in one of the oldest scientific journal:
"Annalen der Physik"
(Annals of Physics).

These papers will probably be dealt in detail in some future nights.

For now suffice to say that these 4 papers transformed the world of quantum mechanics by introducing complex numbers instead of real ones in the wave equations.

Hans Bethe eventually did his doctorate on electron diffraction in crystals.

It is very difficult for me to understand and hence explain the work (his papers) published by Hans Bethe as they involve both higher mathematics and advanced physics.

Take for instance his paper published when he was just 23 working at Stuttgart:
"The Theory of the Passage of Fast Corpuscular Rays Through Matter."

It used Max Born's interpretation of the Schrödinger equation and Fourier Transformation to arrive at what is now known as the Bethe formula.

This formula gives the mean energy loss per distance travelled by fast-travelling charged particles such as protons or alpha particles through matter.

Such knowledge is of little interest to an average ape even though it is a very accurate description of the behavior of nature at its deepest level.

Following short stints at Frankfurt and Stuttgart, Hans went for multiple postdoctoral research fellowships:

One was Cavendish Laboratory under Ralph Fowler (an astronomer) at the age of 24.

Next year he worked at Enrico Fermi's Laboratory in Rome.

Over there he developed something that is now known as Bethe ansatz, a highly technical mathematical physical concept.

An ansatz is a method of studying a physical system by asserting certain starting.  equation (s), theorem(s) or value (s) that would describe a mathematical or physical problem or solution.

Bethe ansatz is a method of finding exact solutions for the eigenvalues and eigenvectors (Eigen is German for "characteristic") of certain one-dimensional quantum many-body models.

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Good night mon ami and my fellow cousin ape.




As you can see, it is a highly technical subject even for a physicist 


Tuesday, September 27, 2016

September 27, 2016 Tuesday

Bedtime Story



Hans Bethe and Arnold Sommerfeld



Hans Bethe after his schooling, majored in Chemistry from the University of Frankfurt.

There in the laboratories he realized that he was a poor experimentalist.

At the same time he found out that he enjoyed advanced theoretical physics.

His physics mentor at the university Karl Meissner counselled Hans to join a university that had a better physics department.

Under Meissner's recommendation, in 1926 at the age of 20, Hans found himself at the University of Munich under the mentor ship of the legendary German professor Arnold Sommerfeld.

Sommerfeld if you recall had gifted to quantum mechanics the second and the fourth quantum numbers, namely the azimuthal quantum number and the spin quantum number.

Quantum numbers is (or are) a complete numerical description of electrons in an atom.

In general, quantum numbers is capable of describing any formal system with discrete set of integers or half integers.

Beside his original contribution to quantum mechanics, Sommerfeld like J. J. Thomson had a gift for picking out talents and honing and carving them out to become original physicists.

Sommerfeld himself when young was assistant to the great German mathematician Felix Klein whose notes he would jot down assiduously during lectures and later write them up for the mathematics reading room.

Such was his zeal for teaching that Wilhelm Roentgen who was the director Physics Institute in Munich appointed Sommerfeld as the professor and director of the newly established Theoretical Physics Institute at the University of Munich.

If you recall my past bed-time stories, all through the 1800s it was the experimental physics in Germany that held the reign of scientific advancement and progress.

By the end of 1800s and early 1900s, thanks to men like Sommerfeld in Munich and Max Born in Göttingen the tables were turned upside down.

For the first time mathematical physics or theoretical physics became the prime over.

Experimental physics would serve largely to verify the predictions made by mathematical physics.

Einstein once told Sommerfeld:
"What I specially admire about you is that you have, as it were, pounded out of the soil such a large number of young talents."

Sommerfeld nurtured a string of brilliant mathematical physicists one of whom was Hans Bethe.

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Good night mon ami and my fellow cousin ape.




       Arnold Sommerfeld with Chandrasekhara Venkata Raman


Azimuthal Quantum Number

Monday, September 26, 2016

September 26, 2016 Monday


Bedtime Story


The German-Hindu Conspiracy in the World War I 


Hans Bethe was born in 1906 in such a German Empire and in such an Europe where nearly every nation or empire wanted to acquire resources (land and people) by means of war.

His father Albrecht Bethe  was an associate professor of physiology at the University of Strasbourg.

Quite to my surprise he reproduced just once, giving birth to a gem of a child.

Albrecht Bethe eventually went on to become the head of a whole new institute of Physiology in Frankfurt that was set up in 1915.

It is a noteworthy point that even as the terrible mother of all wars was being unleashed in Europe from 1914 onwards, the German Empire continued to invest in basic sciences such as physiology.

Young Hans suffered a bout of tuberculosis at the age of 10 in the year 1916.

1916 was also the year of the Battle of Somme and the beginning of the excruciatingly prolonged trench warfare.

Most of us will not be aware that at this time the German Foreign Office with support from the Ottoman Turkey and the Irish Republican Movement approached the Indian Army under British.

Secretly.

The German mission was sent to Afghanistan to foment unrest and instigate uprising in the ranks of the Indian Army similar to the famous Sepoy Mutiny of 1857.

Quite to everyone's surprise, including the British, both the leaders from the Indian National Congress and the Indian Army (from Punjab to Singapore) showed an unprecedented loyalty and good will to their British Masters.

Some of the groups who did hatched the mutiny such as the Indian Revolutionary Underground, the Ghadar Party in the United States/Canada and the Indian Independence Committee in Germany were thwarted by the British Intelligence who had infiltrated these groups.

This not-so-famous Hindu-German Conspiracy as well the Ghadar Party (Ghadar is a Urdu word derived from Arabic meaning revolt or revolution) ended in abject failure.

All the key figures were arrested and the planned February Mutiny of 1915 never really got the chance to take off.

The British Raj lashed back at its prime colony by passing the draconian and oppressive Rowlatt Act of 1919.

It allowed for indefinite detention and incarceration without trial or judicial review.

This was followed by the Jallianwala Bagh Massacre of April 13, 1919.

Nearly 1.3 million soldiers and labour from the subcontinent had spread over Europe, Africa and the Middle East and fought loyally for their masters.

Around 48,000 were killed and 65,000 injured in the service to the British Empire.

The Indian subcontinent unquestionably was the jewel in the crown of the British Empire.

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Good night mon ami and my fellow cousin ape.


In the center is the exiled Indian Prince Raja Mahendra Pratap with the German and Turkish representatives in Kabul, Afghanistan 1915

Sunday, September 25, 2016

September 25, 2016 Sunday

Bedtime Story


Even when world population was less than 1000 million, world resources was short



Correlating the world history between 1800s and early 1900s with the microbial behavior discussed previously makes for a fascinating exercise.

In the early 1800s even when the world population was less than 1000 million (today India alone is 1200 million mouths), the empires were jittery about resources.

The scarcity was further compounded by greedy and ambitious monarchs such as Napoleon Bonaparte, Otto von Bismarck and the likes of these.

The Franco-Prussian war of the 1870 had already set the tone for things to follow.

It was fought by the Kingdom of Prussia (which included present day Germany, Poland, Russia, Lithuania, Denmark, Belgium and the Czech Republic) along with the North German Confederation against the second French Empire.

The British and French Empires took the early lead in warring and colonizing thanks to their early industrialization.

Germany was always lagging behind.

Once after it united as a single entity in 1871 Germany began to seriously pour in significant economic resources to build the German Imperial Navy to compete and be a bulwark against the mighty British Royal Navy.

It was a case of that good old arms race for the world naval supremacy.

Britain seeing the dangerous ambitions of Germany began to get snug and cosy with France (its formal enemy) and Russia (never a good friend of the British Empire) forming an alliance that is known as the Triple Entente.

Remember that all 3 were empires themselves having overlapping interests.

Germany not to be left behind and alone reached out to the Austro-Hungarian Empire and the Kingdom of Italy.

As if the West and the Central Europe was not enough of a mess already, there entered a third player that would initiate a chain of events leading to the mother of all wars.

It was the Balkans rightly called the "Powder Keg of Europe".

The Balkans is a patch of land (peninsula to be accurate) in South East Europe that is surrounded by Adriatic Sea in the west, Mediterranean and Marmara seas in the south and Black sea in the east.

Up north it is attached to the land mass of East Europe.

The problem with the Balkans is that politically and geographically it is stuck between frying pan and fire.

Almost all the major powers of that time namely the Russian Empire, the Ottoman Empire, the German Empire, the Austro-Hungarian Empire, Kingdom of Italy and British Empire exerted their spheres of influence and even staked claim over it.

It was yet again a classical case of struggle for limited resources by too many players.

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Good night mon ami and my fellow cousin ape.



The Franco-Prussian War of 1871 settled the "German Question" and set the stage for its imperialistic ambitions



The Franco-Prussian war of 1870-71 killed around 140,000 on the side of the French Empire and around 29,000 on the side of the German Empire

Saturday, September 24, 2016

September 25, 2016 Saturday


Bedtime Story


From Quorum Sensing emerges Intelligent Decision Making 



4. Calling Out the Artillery:
It is a mechanism that has been very extensively studied.

It involves production and secretion of antimicrobial compounds that can either repel or kill other microbes.

To produce sufficient quantity of it concerted effort of entire population is needed.

This is achieved by what is known as quorum sensing.

It is a technique of decision making in a decentralized system.

Quorum sensing in a population is possible as long as the following 2 conditions are fulfilled:

(a) Individuals have some means of determining or "know" the number of other individuals in the group

(b) They have a standard response once a certain threshold number of individuals has been attained in that group.

Quorum sensing forms the basis for coordination within a colony of microbes for behaviour such as biofilm formation, virulence and antibiotic resistance.

5. Jamming the Radar:
This is a mechanism that disrupts quorum sensing and thus the coordination in a rival colony of microbes.

This is achieved by production of certain specific enzymes that can disrupt intra group signalling which depends on diffusion gradient of enzymes.

Acyl-homoserine lactones (AHLs) are a widely used group of signal molecules that can destroyed by at least 3 groups of enzymes: lactonases, acylases and  oxidoreductases.

These are the 5 methods used by microbes to contest and compete for limited resources.

Remember mon ami, the resources in a real world is always limited, finite and distributes unevenly.

A politician or an industrialist or a right leaning economist will seldom ever sell this truth.

Competition for resources is as inherent and as inbuilt in our existence as it is in the colonies of various species and strains of microbes.

There is in essence very little that separates or distinguishes us from the lives of microbes.

It has to be that way.

As Richard Dawkins puts it:
"We are survival machines -
robot vehicles blindly programmed to preserve the selfish molecules known as genes."

Whether the robot vehicle is in the form of gut bacteria or a beautiful feminine hairless ape, it is all the same.

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Good night mon ami and my fellow cousin ape.



Bacteria like us communicate with each other



Biofilm formation on indwelling devises such as catheters




Friday, September 23, 2016

September 23, 2016 Friday

Bedtime Story



Competing for limited resources: Oldest Problem in Biology



Nature is red in tooth and claw.

Life in all its varied forms is based on unmitigated relentless competition.

Human societies and civilizations only reflect this uneasy bitter truth.

The similarity in the social behavior of microbes is remarkably similar to that of the great apes.

Microbes exhibit the same phenomenon of kin selection or kin altruism that we display towards our families and close relatives.

Microbes too display social cheating which is ubiquitous and widespread in us apes.

When it comes to battling for resources, yet again microbes deploy 2 basic strategies:

A. Scramble

B. Contest

Scrambling involves rapid utilization of the available resources without directly confronting the competitors.

Scrambling combines space occupation along with rapid growth.

The famous biologist E. O. Wilson gave the analogy of street urchins rushing in to gather falling coins falling from purse of a wealthy fat baroness.

To my mind, there is no better example for the scramble competition than the Scramble for Africa by the world powers that started in 1880s and continues till date.

The second strategy of Contest involves direct interaction with the rivals along with cooperation with clones of same or similar genetics.

This results in population-level strategy of contest between colonies of slightly different genotypes.

The methods of Contesting can be divided into 5 subtypes:

1. Protecting the Supply Line:
A beautiful example is the production of high-affinity, iron scavenging or chelating molecules called siderophores.

The microbes that produce it divert the supply of iron (an invaluable element In many heme proteins including cytochrome P450) to themselves.

2. Taking and Holding the High Ground:
Is relocating and taking over a site of high nutritive value.

Microbes do so by the production of novel adhesins and receptors that literally allows them to anchor over a desired environment.

Lactobacilli which thrive in the gut of us apes and most animals (they don't consider us apes special), produce surface gylcoproteins that allow them to get a good hold on to the epithelial cells of intestines.

This prevents other bacteria such as Salmonella species or E. coli gaining control.

3. To Fight or Flee:
Where motility is the chief weapon of offense or defense.

Pseudomonas aeruginosa uses its quick mobility to outgrow and blanket colonies of Agrobacterium tumefaciens.

We shall be looking at 2 more strategies in the nights to come.

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Good night mon ami and my fellow cousin ape.


Culturing microbes on the MacConkey agar




Thursday, September 22, 2016

September 22, 2016 Thursday

Bedtime Story



Industrialization needed resources



The Berlin Conference of November 15, 1884 was called upon to minimize jostling for the world resources by the powerful and greedy masters of the planet.

But mon ami, division of the world resources among its people or nations is a zero-sum game.

It is precisely like cutting a cake as was depicted in the cartoon.

Taking a larger piece reduces the amount left over for the others.

Germany sharply rose as an Industrial and economic power house after its unification and foundation of the empire in 1871.

In fact, all the European nations, the United Stated and Japan began to rapidly industrialize simultaneously as they saw the benefit of implementing the scientific revolution on a public scale.

Industrialization is cool.

Yet as is well known, everything comes at a cost; an important concept in biology, economics and cognitive decision making.

Industrialization entails building roads, laying down railway tracks, laying underground pipes both for the flow of clean water and sewage to and from every house, setting up of large factories and so on.

You can very well imagine the colossal resource required if it is done for every nook and corner of a country (as is seen in most developed countries).

Even today countries such as India, Russia, Brazil and other third world countries are struggling with the problem of crumbling infrastructure.

Supply of clean water and sewage/toilets with running water to even half of their populations is an unthinkable proposition for these nations with exploding humanity.

There is no way that those tiny nation states like Britain, France or Germany would have done it from the resources lying within their borders.

So how did these powerful nation states behave when faced with the dilemma of limited resources and expanding needs given that industrialization inescapable?

Exactly like microbes!
Yes Sir!
Unicellular life!

This wonderful paper by Michael Hibbing et al published in the Nature Reviews Microbiology in 2010 titled:

Bacterial Competition: Surviving and Thriving in the Microbial Jungle

gives a lucid account how microbes tackle the problem of limited resources.

Their similarity to human behavior is most eerie and uncanny.

We shall discuss this behavior of microbes in context to our recent history in the nights to come.

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Good night mon ami and my fellow cousin ape.
















Wednesday, September 21, 2016

September 21, 2016 Wednesday


Bedtime Story


Hans Bethe and the story of Germany


Hans Bethe if you recall who was made the second author of the famous Alpher-Bethe-Gamow paper really had nothing to do with the paper.

Though later on he made a tremendous contribution to get it right what was incorrect in that paper.

Hans was born in Strasbourg, Germany when the country was actually the German Colonial Empire (1884-1918).

Those days in late 1800s most "developed" nations of Europe, Russia, Japan and even the United States considered acquisition of colonies (forcefully occupying a foreign country and subduing/ exploiting its people) a hallmark of a mighty and successful nation.

Just like owning many servants is a sign of wealth and prosperity in India.

Germany as history shows always played catch-up relative to the other European powers.

This is so because before the 1871 unification of small German states under Otto von Bismarck, Germany was unsure about its own identity in Europe.

In the 1800s and before, Central Europe where Germany was spoken comprised of more than 300 entities.

These entities ranges from small cities to large kingdoms such as the Holy Roman Empire, Hapsburg Empire, Kingdom of Bavaria, Kingdom of Prussia and so on.

Those days the French Empire of the aggressive and ambitious Napoleon Bonaparte was a constant threat to other European nations.

In fact, if Napoleon had not spread our thinly with his warring exigencies over Poland, Iberian Peninsula and eventually the disastrous invasion of Russia in 1812, it very well may have turned out that today's Germany would have been a part of France.

This is yet another example that so much of our present is a result of succession of historical, evolutionary and cosmology random chance events that are way beyond anyone's control.

Anyway, once under the chancellorship of Otto von Bismarck and King Wilhelm I the Germans were united and their "European Problem"solved, their imperialistic lust took off.

A nation needs resources and wealth to become powerful which was lacking in tiny Europe but abundant in Asia, Africa and Pacific which were busy fighting their own internal wars.

This was exactly the case with South Asia or the Indian subcontinent.

1881 saw the "Scramble for Africa" which was the era of New Imperialism.

Its chief perpetrators were the European powers, the United States (which itself was a colony just a century ago) and the Empire of Japan.

It was in the Berlin Conference of 1884 that the powerful nations set out formally to cut open the African pie.

For them Africa was an open-for-all territory that was ripe for exploration, trade, settlement and plunder.

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Good night mon ami and my fellow cousin ape.



The Scramble for Africa began systematically and with great earnest after The Berlin Conference 1884-85 


The Berlin Conference was organized by Otto von Bismarck on November 15, 1884 where head of 14 countries were invited.

United States
United Kingdom
Russian Empire
Ottoman Empire
German Empire
Austria-Hungary
Sweden-Norway
France
Belgium
Denmark
Italy
Portugal
Spain
Netherlands  


The idea of the conference was to distribute the pie with minimum mutual damage and retribution as the German imperial ambitions frightened both France and British


Tuesday, September 20, 2016

September 20, 2016 Tuesday

Bedtime Story



Gamow settles in America and makes the most of it



Gamow after the famous Alpher-Bethe-Gamow paper went on to publish 20 more in cosmology.

He used the solutions to Einstein's field equations of both Alexander Friedmann and Georges Lemaitre describing the early universe as homogeneous (statistically), isotropic and non static.

In his papers he worked on the formation of elements via nucleosynthesis and formation of galaxies by condensation of matter.

He had initially argued that all the natural elements in the periodic table would have been synthesized right at the time of big bang (give and take few thousands of years).

Fred Hoyle, another star in the history of cosmology, disagreed.

Just like Alpher and Gamow had taken the world by storm with their radical ideas of the early universe, so did Fred Hoyle and his team of brilliant theoretical physicists and cosmologists.

Gamow later had to agree with Fred Hoyle that elements heavier than lithium could not have been synthesized early in the universe.

They would need extreme conditions provided by the thermonuclear reactions occurring in the star and later in the exploding supernovae.

In a later 1953 paper Gamow estimated the temperature of the leftover background radiation to be 7 Kelvin.

This turned out to be double that of the value that is currently agreed upon.

All the three men, Ralph Alpher, George Gamow and Robert Herman were left piqued and felt blotted out when no credit was given to them in 1965 when Penzias and Wilson made that astounding accidental discovery.

The names of the three found no mention in the 1965 papers either that of Penzias/Wilson Bell Lab team or that of Robert Dicke/Jim Peebles team of Princeton.

Gamow, like many great physicists, later turned his attention to the problem of biology; and came very close to the correct solution.

When in 1953 the double helical structure of DNA was revealed, Gamow wondered how the 4 nucleobases adenine, guanine, cytosine and thymine controlled amino acid synthesis.

He proposed that there got to some kind of code  probably with 3 bases coding for one amino acid.

His idea helped Crick and later others in solving this problem of the genetic code.

In 1954, he along with Watson former a RNA Tie Club that had 20 members to correspond with the 20 amino acids.

Gamow later went on to write many popular science books of which Mr. Tompkins series went on to achieve great fame.

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Good night mon ami and my fellow cousin ape.



Girls, Genes and Gamow : By James Watson


Mr. Tompkins probably got greater fame than his creator 

Monday, September 19, 2016

September 19, 2016 Monday

Bedtime Story



Gamow Flees Stalin's Great Purge



Soviet Union in spite of its lofty ideals of socialism and communism can be an extremely toxic place for an innovative, hardworking and free thinking personality.

America, no matter how evil and imperialistic it is portrayed as, is a most livable country.

Particularly for a downtrodden, oppressed and a coloured immigrant who would be an alien minority in a new country.

I say this from my very own personal experience having lived a substantial time in both these two nations.

Soviet Union in 1928 under Stalin imposed forced collectivization of farms resulting in pestiferous famines that led to death of millions.

Those who survived were despatched away to Gulags for forced labour as punishment.

1930s was a witness to Stalin's Great Purge or the Great Terror that involved political and ideological repression with the aid of Soviet Secret Police NKVD.

A person like me would certainly have been crushed and broken in that kind of environment (and perhaps I was).

Gamow would have agreed with me.

Hence from 1930 onwards when he just 26, he made several attempts to flee the country where he simply happened to be born without any choice or permission.

(In this respect most parents are guilty of such a crime.)

Finally in 1933, at the age of 29 he got his chance.

The pretext was participation in the 7th Solvay Conference which is held in Brussels near about every 3 years.

He insisted on taking his wife along and the Soviet authorities with great reluctance granted them their passports.

Once in Brussels, Gamow took help of Marie Curie and other colleagues to extend his stay.

From there, his next halt was at the Curie Institute, Paris followed by a temporary position at the University of London, England.

Finally in 1934, at the perfect age of 30, Gamow made it to America where anyone from any background and any social class was free to pursue the American Dream.

Which Gamow did and how!

America welcomed him openheartedly by immediately giving him the position of professor at the George Washington University located at Foggy Botton, District of Columbia.

Once here, his interests shifted to cosmology and astrophysics, particularly the early history of both the solar system and the universe.

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Good night mon ami and my fellow cousin ape.



A sample of executions occurring during The Great Purge in 1930s




Matvei Bronstein one of the Three Musketeers and a pioneer of Quantum Gravity was executed in February of 1938 during the Great Purge  

Sunday, September 18, 2016

September 18, 2016 Sunday

Bedtime Story



Gamow Explains Alpha Decay via Quantum Tunneling


Perhaps the most colorful and vibrant personality in the saga of the Big Bang and nucleosynthesis story is the Soviet-Russian-Ukrainian-American theoretical physicist and cosmologist George Gamow.

He was born in Odessa, Russian Empire (the city now lies in the Ukrainian part of the Black Sea) in 1904 to parents both of whom were teachers.

His early education took place in Odessa though he shifted to the University of Leningrad (St. Petersburg) in 1923 at the age of 19.

Here he encountered Alexander Friedmann and was fortunate enough to study under him for some time (Friedmann died young in 1925).

In the university he befriended 3 bright minds and formed a club known as The Three Musketeers.

Those 3 were:

1. Lev Landau: who made fundamental contributions to theoretical physics

2. Dmitri Ivanenko: another theoretical physicist who always remained at the forefront of latest physics

3. Matvei Bronstein: a pioneer in quantum gravity who during the Great Purge under Stalin was executed at the young age of 32.

These four young physicists would gather and study and scrutinize the latest papers in quantum mechanics.

From St. Petersburg Gamow moved and worked in almost all the great centers of theoretical physics of that time such as:

Göttingen, Germany

Niels Bohr Institute, University of Copenhagen

Cavendish Laboratory, Cambridge under Ernest Rutherford

He studied the process of alpha decay (a type of radioactivity) wherein an atomic nucleus spontaneously emits an alpha particle and transforms into another atomic nucleus that has its atomic mass reduced by 4 and atomic number reduced by 2.

Example:

Uranium 238 decaying to Thorium 234

238 U 92 ~ 234 Th 92 + 4 He 2

238
92
U
 → 234
90
Th
 + 4
2
He



Before Gamow it was not clear how the alpha particle could break free from the strong potential well.

The energy required is too high to enable this reaction to occur spontaneously.

Gamow used the principle of quantum tunneling that allows particles to surmount an energy barrier that is not explainable using classical physics.

Gamow's solution was mathematical which he derived by solving the Schrödinger equation for a model nuclear potential.

From this he derived a relationship between the half-life of the alpha particle and the energy of the emission.

Stay tuned to the voice of an average storytelling chimpanzee or login at http://panarrans.blogspot.in/

Good night mon ami and my fellow cousin ape.





Saturday, September 17, 2016

September 17, 2016 Saturday

Bedtime Story



The First to Predict Cosmic Microwave Background Radiation


When Ralph decided to send his dissertation for publication as a paper, Gamow had rather a wicked idea blessed as he was with a naughty sense of humor.

He noticed the names Alpher and Gamow rhymed with the Greek alphabets alpha and gamma.

Not to leave out beta and make a complete alpha, beta, gamma Gamow in the authorship added the name of Hans Bethe as the second author.

He actually added Hans Bethe (in absentia).

When Bethe was sent a copy of the paper before publication, he liked the science of the paper and decided to cancel out the words "in absentia" after his name.

Everyone thought it was a great joke except for Ralph Alpher who felt cheated.

Just as the famous dissertation went for publication in 1948, Ralph Alpher came across another physicist at the APL of Johns Hopkins.

He was the 34-year old Robert Herman, another forgotten pioneer.

These two set out to work on another paper in cosmology in which they proposed that the very early universe would have been a hot opaque plasma of ionized gas.

The radiation coming from it should behave like that of a black body.

A black body absorbs all EM (electromagnetic) radiation that falls on it.

Being in thermodynamic equilibrium with its surrounding, it emits radiation back at the same rate.

This radiation has a specific spectrum that depends solely on its temperature.

The early universe had free electrons everywhere as they were still unable to "stick" to the deuterium and alpha particle nuclei.

These free electrons would have impeded the movement of photons preventing the travel of radiation.

When the universe got 350,000 years old, then it had expanded and cooled sufficiently to allow the electrons to combine with atomic nuclei resulting in the elemental hydrogen and helium that we see now all over.

This then also allowed the photons and hence the radiation to travel unimpeded.

This radiation, Alpher and Herman predicted, should now have cooled down to 5 Kelvin and must be present all around us as a black body residual radiation of the Big Bang.

The paper was largely ignored until 2 very ordinary engineers working at Bell Laboratory Arno Penzias and Robert Wilson accidentally tripped on to this cosmic microwave background radiation.

Eventually however, quite late in 1993, their work was finally recognized and they were bestowed with the prestigious Henry Draper medal from the National Academy of Sciences.

They later went on to write the whole account in a book titled:
"Genesis of the Big Bang"
that was published in 2001.

Stay tuned to the voice of an average storytelling chimpanzee or login at http://panarrans.blogspot.in/

Good night mon ami and my fellow cousin ape.



                                           Genesis of the Big Bang



The cosmic microwave background radiation has a thermal black body spectrum at a temperature of 2.72548 +- 0.00057 K

Friday, September 16, 2016

September 16, 2016 Friday

Bedtime Story



What the Alpher-Bethe-Gamow paper proposed



The idea postulated in the dissertation was that during the initial moments after the singularity (we are talking in terms of seconds), the temperatures were extremely high and all that existed then were a sea of neutrons (matter) and photons (radiation).

The neutrons then began to decay into protons and electrons by the now well known process of beta minus decay.

Alpher, Gamow and we apes were aware of only these subatomic particles then.

As per Alpher's calculations, the resulting ratio of protons to neutrons was 7:1.

Proton and neutron can stick together (due to the strong force that exists between quarks) and if they got electrons going around them, atoms form.

An electron going around one bare proton results in a hydrogen atom.

But electrons could not "stick" to the protons or to the neutrons as the universe then was incredibly hot.

High energy photons were knocking them out.

One proton could stick to a neutron forming deuterium, one of the stable isotopes of hydrogen.

Deuterium would have been stable 180 seconds after the singularity when the temperature had dropped down to 10^9 Kelvin.

All the neutrons then combined with protons to form deuterium.

2 deuterium particles can stick together to form an alpha particle which is the nucleus of Helium atom.

Some of the deuterium particles that did not fuse together and has got left over since then.

So by 17 minutes or so the universe had alpha particles and deuterium but no neutrons.

It remained that way for 350,000 years or so.

By then as the universe expanded the temperature dropped down so much that now it became possible for electrons to "stick" to the protons and alpha particles giving rise to elemental hydrogen and helium.

Alpher went down to calculate the ratio of elements that would be formed depending on their atomic weight.

He found the Helium mass fraction to be 0.2999.

This predicted roughly a quarter of the universe would be made up of helium atoms and three-fourth would be made of hydrogen by weight.

This prediction was proven true experimentally which made the paper so valuable.

This paper went on to predict that all the elements would have been produced during the Big Bang by this process of neutron capture.

This part turned out to be wrong as fusion beyond Helium is inefficient.

Stay tuned to the voice of an average storytelling chimpanzee or login at http://panarrans.blogspot.in/

Good night mon ami and my fellow cousin ape.


A detailed flowchart of the nuclear events in the first few seconds and minutes


Difference between the Big Bang Nucleosynthesis and Stellar Nucleosynthesis



The 4 different nuclei of elements that were formed in the first few minutes (note that electrons were unable to "stick" to them, not until 350,000 years had gone by) 

Thursday, September 15, 2016

September 15, 2016 Thursday

Please scroll down below to read the bedtime story




On human apes by the storytelling chimpanzee



My view of human apes


Let me be clear at the onset of my view. I am not proud of my species which calls itself Homo sapiens.

You just need to look our sorry history of violence, warring and massacres over power, resources and religion.

I think, for the most part, the human ape thinks, acts and reproduces as do his great ape cousins (they mate, have family, have culture etc. as shown by studies of Jane Goodall, Desmond Morris and many more)

Our evolution of higher faculties


Yet, for an ape, we have come a long way forward. The journey has been slow and arduous.

The first ape like humans probably arose (quiet literally) on their two feet some 5 to 7 million years ago (that is 50,000 to 70,000 centuries ago).

The great apes as a family go back 15 million years.

Somewhere down the line we developed imagination, curiosity, the ability to consider “What if?”

These qualities of imagination, curiosity and abstract thinking are vital components of storytelling so that when developed, a mere mention or even the thought of a word can evoke artificial, imaginative or real worlds in the mind.

Other animals too have traits of intelligence


We are not certain if our cousin great apes have it or not, and if they have, to what extent it is developed.

Curiosity is certainly very common in animal kingdom. 

It is a human hubris to think that we are sole possessor of this facility.

Other animals are as curious as us including our cousin apes, cats, rodents to name a few?

Curiosity is an inquisitive thinking that involves observation, exploration, investigation, learning and finally changes in behavior.

Curiosity has survival and reproductive value which is essential for success of DNA transmission, the raison d’etre for any kind of life based on carbon and DNA.

Curiosity involves several neurological aspects such as motivation and reward, attention, memory and learning.


Our crippling shortcomings



The other thing that we humans need to be aware is that we are in the end apes and very flawed apes at that.

No doubt we have higher intelligence and contemplate abstract thinking.

Yet, our evolutionary mind uses principles that had served us well when we were hunter-gatherers in the African savannas but now do us grave injustice.

They are termed cognitive fallacies.

The list of these heuristics (mental shortcuts), biases, is devastatingly huge and long.

They become a fertile ground for the breeding of irrationality in human apes.

Worse, irrationality is highly contagious.


Classification of cognitive biases



These cognitive biases are divided into three categories:

1. Decision making and belief biases:

    There are more than 80 of these.

    One good example is the bandwagon effect or the herd mentality. This explains how easily a temple, or church or a statue gets tagged as “lucky”.

2. Social biases

    There are at least 25 of these.

    The classic one being the just-world hypothesis also known as the moral luck. It is a belief that good stuff happens to virtuous and ill happens to the diabolical, deservingly of course.

    Another good example is the Barnum effect (closely related to subjective validation) wherein an individual considers a general and a vague statement highly specific to his or her own personality.

   Example: Disciplined and self controlled outside, you tend to be worrisome and insecure inside.

   Entire chicanery of astrology, palmistry and astrology are based on this one bias.  

3. Memory errors and biases

    There are at least 60 of them

 The peak-end rule is a suitable example. It is the assessment of any experience by an individual largely on how they felt it at its peak and at its termination.
 This has a special significance for medical procedures and surgeries.


Limitations of curiosity, logic and abstract thinking



You will realize that just being curious and having the ability of abstract thinking is not enough.

These two generally end up in giving rise to either philosophy or worse, religion.

These traits alone would very likely have us end up in creating a world view that is largely hopeful, helpful and endearing but factually incorrect.

This in fact did happen for most of the time in human history.

Added with these two, if one begins to apply logic and proofs, the brain is capable of generating powerful mathematics. 

Yet, all these devises and tools namely curiosity, imagination, logic and mathematical proofs have proved themselves deficient in curbing our remarkable ability to fool ourselves.


Experimental Science is the best tool ever devised to understand reality



The only tool and the best method that we humans came up with understanding reality is experimentation, particularly well controlled, repeatable verifiable experiments that can minimize the experimenter’s bias.

In medicine, the gold standard of drug testing for its efficacy and safety is the placebo controlled double blind clinical trial.

It is not an easy task to conduct an original experiment.


Education’s Biggest Failure



Our school education’s profoundest failure is exactly this.

It does not inculcate either questioning or original thinking or more specifically critical thinking.

We fail to teach our students the idea of how to propose a hypothesis and go about testing it.

Our schooling fails to provide to even the best outgoing student the notion of conceiving an original experiment to prove or disprove an idea.   

Only few people are good experimentalist, meaning they take care to isolate their study from events that can undue influence its outcome.

The most important aspect about the experimental findings is that it should be repeatable, verifiable by other people who repeat them under similar conditions in other places.

It is the one biggest universal failure of education system all over the world.

Education is currently seen as a way to attain professional career and job security which is not bad per se.

But something very important has been lost.

Do we encourage a student to write an original paper?

Do we encourage a student to ever lay out a plan for considering an original experiment?

In fact, in our education, do we even mention that so many unknown things remain to discover.

May be it is so that there is now so much to know that it overwhelms a young mind.

At least most young minds.


The reason for the failure of education



What prevents us from imparting the type of education we often know about, speak about but fail to carry out?

You will be surprised at the answer.

It is overpopulation; too many of us human apes.

If someone were to ask me what is the key problem today, I would say that we are simply too many of us today.

India or South Asia is an extreme example but almost all the nations face this hideous calamity.

Are nation states able to provide clean air and water to their citizens?

Are they able to provide a basic housing to their citizens?

Are they able to provide even basic level healthcare to their citizens?

What about jobs?

Many argue between capitalism, socialism, mixed system and so on and so forth.

I think they keep missing the key issue.

Denial is probably the right word.

Such a populace simply cannot be given the fundamental rights as enshrined in the constitutions of most nation states. 

Most would not sit to listen to this and may get up and leave in protest.


Stating the problem



But let me make my case.

Just feeding, giving clean water and jobs is not the way we should be looking at the citizens of the world; though even that itself is a herculean task and even the most developed nation states are grappling with the problem.

I want to go beyond this.

Why has education, the process of acquiring knowledge become such a painful task for most young people?

Let us see this step by step.

For starters, every child right from a day she is born needs a decent health care and nutrition.

The idea is to get very good schooling.

Good schools are few and the race starts right here.

Only very few percentage of humans born will get good schooling.

Second step, after the school, it is the college.

The idea of scoring top percentages is to get into the best colleges.

We all know that in general in any country, including the United States, only a tiny percentage of colleges or universities offer a life enhancing and transforming program.

Good education needs great teachers.

Great and dedicated teachers are a rarity as a society can afford to pay and reward only a handful of good teachers, professors.

Following that, we have the problem of jobs or a professional career.

Here again one encounters a cut throat competition and only a few will land up with a satisfactory job.

As it is, most of us humans are average and really not very productive for a society.

In fact, most of us can be or turn out to be a burden for the society.

A planet that has fewer people, can be better educated, can be given better lives, and can be given better policing /security and a speedier and effective justice.

Crime itself will come down.

The lesser we are, the more we will care for each other.

Moreover, more productive and educated people are more likely to contribute funds not only for the resources needed to run a society but to higher pursuits of sciences and mathematics.

This idea is extremely repulsive and disgusting to nearly everybody as it goes against our biological drive, our most primal instinct.

But what needs to be done must be done.

Otherwise we will be doomed to mediocrity and worse, nightmarish suffering that is visible all around us.

Someone asked me the one biggest mistake we have made.

I think it is this.

We have allowed runaway breeding of ourselves.

If we wish all schools to impart scientific teaching and inculcate scientific methods, we need to have fewer of them very good ones with better facilities with fewer pupils to care after.

Just being a few would increase love and tolerance for each other and further our cooperation. 


Going one step further



In this context, another important pops up.

We are aware that resources are scare, may it be for education, for health, for research, for fuels, for energy.

We, if are intelligent and rational enough, must plan our death once we realize that our contribution to the society is nil.

After that, we become a parasite and a hindrance for the younger generation who exist and who are to come.

This is one of the biggest prices we are paying for the success of medicine.

Ageing and geriatric diseases are taking a huge toll on the national economies, especially of the developed world where the state bears the expenses of the early to a large extent.

Finally when the time comes, one needs to embrace death by making death peaceful, planned and curbing our greedy desire to go on and on.


Story Telling Chimpanzee


September 15, 2016

Bedtime Story


On Ralph Alpher



Ralph Alpher is a relatively obscure name considering the fact that he was a white American whose thesis dissertation was legendary for the coverage it got from the press and the print media.

Ralph was born in Washington DC in 1921 to Belarusian Jewish immigrants when America was going through post war depression.

Even as he pursued his bachelor's and masters degree at the George Washington University (GWU), he was bright enough to be working on a contract with the US navy.

All through the world war II, he helped the navy in the development of detonators, torpedoes, ship degaussing techniques and ordinance work that remained classified.

Then in 1944, at the age of 23 he joined the Johns Hopkins University Applied Physics Laboratory (APL) then located at Silver Spring, Maryland not far from the capital.

APL was set up by the US navy in 1942 to conduct research for developing their offensive and defensive war technology.

Ralph met Gamow at the GWU somewhere at the end of 1930s.

Gamow had defected from Soviet Union on the pretext of attending the 1933 7th Solvay Conference in Brussels.

By 1934 he had joined the faculty of the GWU as a professor.

Both Gamow and Alpher had the idea that they had a tenable theory on the origin of elements.

Both needed each other as Gamow was a kind of celebrity famous for giving talks all over the country and outside.

Alpher on the other hand had the mathematical knowledge that Gamow needed to give a solid bearing to his theory.

Alpher dissertation was on the synthesis of the elements immediately after the Big Bang.

It is formulated on the idea of neutron capture in the immensely hot early universe.
(At the Planck time 10-43 secs after the singularity,
the universe was 10-33 cm across and,
the temperature was 1032 Kelvin).

Barely a second after the event, the temperature drops to 1010 Kelvin (universe had inflated to 1019.5 cm).

This is now known as the Big Bang Nucleosynthesis (BBN).

We shall discuss the details of the dissertation in a non mathematical language in the night to follow.

Stay tuned to the voice of an average storytelling chimpanzee or login at http://panarrans.blogspot.in/

Good night mon ami and my fellow cousin ape.








                                                The Physical Review     April 1, 1948