Monday, April 22, 2019


April 22, 2019 Monday

Bedtime Story 


Photoreceptors, Bipolar and Retinal Ganglion Cells


But it is not that each retinal ganglion cell will get input from 100 photoreceptors as this ratio varies from place to place in the retina.

For instance in the fovea that is visually most significant and functional part of the retina a single retinal ganglion cell may get input from as low as 5 photoreceptors whereas in the extreme periphery near a sight known as the ora serrata which is barely used by us on most occasions a single retinal ganglion cell gets input of signals from thousands of photoreceptors.

The bipolar cells when stimulated by the photoreceptors can either be stimulated or inhibited depending upon the type of receptor that is acted upon by the glutamate neurotransmitter that is released from the photoreceptors.

This minor complexity and variability in the response of bipolar cells to the same neurotransmitter glutamate builds in a computation mechanism for decoding color, contrast, edges and direction.

This complexity is further enhanced by horizontal cells and amacrine cells or the interneurons that form complex synapses between bipolar cells and retinal ganglion cells and between photoreceptors and bipolar cells and also between the photoreceptors themselves.

One can consider these different cells and their synapses equivalent to logic gates that form the foundational basis of working of computational machines.

Computer science provides us with a far more superior metaphorical language – perhaps the best and the most apt till date - to under the computational functions of the brain since in the end the brains along with neurons has to a computational device evolved to decode the input streaming into it from the various senses.

To explain the computational mechanism and origin of the functionality of the cells of the retina a concept of receptive field was devised.

The concept of receptive field is not something abstract but extremely definite and precise that can be objectively measured through physiological experiments using brains of other species and microelectrodes.

A receptive field is applicable to a single sensory neuron that defines it area of interest or activity.

This means that there is a limited and specific zone around a sensory neuron (which can be a skin surface or a visual field) and which when acted upon by a stimulus will lead to change in the firing of that neuron.

In the visual system receptive field of any sensory neuron is a volume in the visual space.

This volume varies in different parts of the visual system being the smallest in the fovea which explains the accuracy of vision of fovea centralis but also compromising its visual field.

The average angle of view of a single cone cell in fovea is a miniscule 31.46 arc seconds.

When we consider such a single photoreceptor namely a cone in the fovea right behind the center of a clear natural crystalline ape lens then its receptive field is extremely tiny but will stretch long, in fact infinitely long from the center of the lens to infinity.

Stay tuned to the voice of an average story storytelling chimpanzee or login at http://panarrans.blogspot.com
                              
Good night Mon Ami and my fellow cousin ape.
                           
  
                

             












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Another great educator and a teacher that I am aware of is Professor Subhashish Chattopadhyay in Bangalore, India.

While I narrate stories, Professor Subhashish an electronic engineer and a former professor at BARC, does and teaches real mathematics and physics.

He started the participation of Indian students at the International Physics Olympiad.

Do visit him here:


All his books can be downloaded for free through this link:


For edutainment and English education of your children, I recommend this large collection of Halloween Songs for Kids:




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